I whakaputaina tata nei tētahi rangahau hou ko te taitara "Te Whakamahi i te Pix-2-Pix GAN mō te Whakatikatika Whakaiti PSMA PET/CT Whole-Body e Hangai Ana ki te Ako Hōhonu" i roto i te Pukapuka 15 o Oncotarget i te 7 o Mei, 2024.
He āwangawanga te pānga o te irahiko mai i ngā rangahau PET/CT ā-wāhanga i roto i te aroturukitanga tūroro matepukupuku. I roto i tēnei rangahau tata nei, i whakauruhia e tētahi rōpū kairangahau tae atu ki a Kevin C. Ma, Esther Mena, Liza Lindenberg, Nathan S. Lay, Phillip Eclarinal, Deborah E. Citrin, Peter A. Pinto, Bradford J. Wood, William L. Dahut, James L. Gulley, Ravi A. Madan, Peter L. Choyke, Ismail Baris Turkbey, me Stephanie A. Harmon mai i te National Cancer Institute i te National Institutes of Health tētahi taputapu matauranga horihori (AI). Ko te whāinga o tēnei taputapu he whakaputa i ngā whakaahua PET whakatikatika-whakaiti (AC-PET) mai i ngā whakaahua PET whakatikatika-kore (NAC-PET), ka whakaiti pea i te hiahia mō ngā karapa CT horopeta iti.
"Kei ngā whakaahua PET i hangaia e te AI te kaha haumanu ki te whakaiti i te hiahia mō te whakatikatika whakaiti i ngā karapa CT me te pupuri tonu i ngā tohu tauanga me te kounga o te whakaahua mō ngā tūroro matepukupuku repeure."
Ngā Tikanga: I whakawhanakehia he pūnaha ako hohonu i runga i te hoahoa whatunga whakataetae whakaputa uri 2D Pix-2-Pix (GAN) i runga i ngā whakaahua AC-PET me NAC-PET kua takirua. I wehea te rangahau PET-CT 18F-DCFPyL PSMA (Prostate-specific membrane antigen) o te 302 tūroro me te mate pukupuku repeure ki ngā rōpū whakangungu, whakamana, me te whakamātautau (n 183, 60, me te 59). I whakangungua te tauira mā te whakamahi i ngā rautaki paerewa e rua: te Uara Whakamau Paerewa (SUV) me te SUV-NYUL. I aromatawaihia te mahi whakapae matawai mā te whakamahi i te hapa tapawhā toharite kua whakaritea (NMSE), te hapa tino toharite (MAE), te taupū ōrite hanganga (SSIM) me te ōwehenga tohu-ki-haruru tihi (PSNR). I whakahaerehia e te tākuta rongoā karihi he tātari taumata whara o te rohe e hiahiatia ana. I aromatawaihia ngā tohu SUV mā te whakamahi i te tauwehenga taunga ā-rōpū (ICC), te tauwehenga whakahokinga (RC), me ngā tauira pānga whakauru raina.
Ngā Hua：I roto i te rōpū whakamātautau motuhake, ko te NMSE, MAE, SSIM, me te PSNR toharite he 13.26%, 3.59%, 0.891, me te 26.82. Ko te ICC mō te SUVmax me te SUVmean he 0.88 me te 0.89, e tohu ana i te hononga kaha i waenga i ngā tohu whakaahua tauanga taketake me ngā tohu whakaahua tauanga i hangaia e AI. I kitea ko ngā āhuatanga pēnei i te wāhi o te whara, te mātotoru (ngā waeine Hounsfield), me te tango whara he pānga ki te hapa whanaunga i roto i ngā inenga SUV i hangaia (katoa p < 0.05).
"Ko te AC-PET i hangaia e te tauira Pix-2-Pix GAN e whakaatu ana i ngā inenga SUV e tino rite ana ki ngā whakaahua taketake. Ko ngā whakaahua PET i hangaia e te AI e whakaatu ana i te kaha haumanu pai mō te whakaiti i te hiahia o ngā matawai CT mō te whakatikatika i te whakaiti i te kaha me te pupuri tonu i ngā tohu tauanga me te kounga o te whakaahua."
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E mōhio ana tātou katoa, ko te whanaketanga o te umanga whakaahua hauora e kore e taea te wehe atu i te whanaketanga o tētahi raupapa taputapu hauora – ngā werohanga matū rerekē me ā rātou taputapu tautoko – e whakamahia whānuitia ana i tēnei mara. I Haina, e rongonui ana mō tana umanga hanga, he maha ngā kaihanga rongonui i te kāinga me tāwāhi mō te hanga taputapu whakaahua hauora, tae atu kiLnkMedMai i tōna whakatūnga, kua aro nui a LnkMed ki te mara o ngā werohanga matū rerekē pēhanga-teitei. Ko te tīma hangarau o LnkMed e arahina ana e te Tohu Paerua me te neke atu i te tekau tau o te wheako, ā, e whai wāhi nui ana ki te rangahau me te whanaketanga. I raro i tana arataki, ko tePūwero upoko kotahi CT,Pūwero upoko rua CT,Werohanga matū whakawhiti MRI, meWerohanga matū rerekē pēhanga teitei o te angiographyKua hangaia me ēnei āhuatanga: te tinana kaha me te kiato, te atanga whakahaere watea me te mohio, ngā mahi katoa, te haumaru teitei, me te hoahoa pakari. Ka taea hoki e mātou te whakarato i ngā ngira me ngā ngongo e hototahi ana ki aua waitohu rongonui o ngā werohanga CT, MRI, DSA. Me ō rātou waiaro pono me te kaha ngaio, ka tono atu ngā kaimahi katoa o LnkMed ki a koutou kia haere mai ki te tūhura tahi i ētahi atu mākete.
Wā tuku: Mei-14-2024
